58-97-9

  • Product Name:UMP
  • Molecular Formula:C9H13 N2 O9 P
  • Purity:99%
  • Molecular Weight:324.184
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Product Details

Veterinary Grade Feed Additives 5'-Uridylic acid(UMP) 58-97-9

  • Molecular Formula:C9H13 N2 O9 P
  • Molecular Weight:324.184
  • Melting Point:202°C (rough estimate) 
  • Boiling Point:°Cat760mmHg 
  • PKA:pK1:6.63 (25°C) 
  • Flash Point:°C 
  • PSA:181.12000 
  • Density:1.865 g/cm3 
  • LogP:-2.73490 

Feed Additives 5'-Uridylic acid(UMP) 58-97-9 Usage

5'-Uridylic acid(UMP) a nucleotide that is synthesized from uridine. It is used in foods such as infant formula to as a method of increasing uridine levels in blood. UMP had an important impact on the levels of metabolites and endocrine hormones in pre-weaning and young goats.

InChI:InChI=1/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

58-97-9 Relevant articles

Effects of 5′-uridylic acid feeding on postprandial plasma concentrations of GH, insulin and metabolites in young calves

K Katoh, K Yoshioka, H Hayashi, T Mashiko1 , M Yoshida, Y Kobayashi and Y Obara

Journal of Endocrinology (2005) 186, 157–163

Postprandial changes in plasma concentrations of GH, insulin, IGF-I, leptin and metabolites were compared between young Holstein bull calves fed with milk alone (control group) and with milk+5-uridylic acid (UMP) (UMP group). UMP (2 g/day) was given with milk at 0830 h and 1530 h for 11 days from the 4th to the 14th day after birth.

Significance of the enzyme complex that synthesizes UMP in ehrlich ascites cells

Thomas W. Traut

Archives of Biochemistry and Biophysics Volume 200, Issue 2, 1 April 1980, Pages 590-594

The de novo biosynthesis of pyrimidine nucleotides is completed by two sequential enzyme activities that convert orotate plus 5-phosphoribosyl-1-pyrophosphate to orotidine-5′-monophosphate (OMP) and PPi and then decarboxylate OMP to produce 5′-uridylic acid.

58-97-9 Process route

yeast RNA

yeast RNA

cytidine monophosphate
63-37-6,30811-80-4

cytidine monophosphate

5'-Uridylic Acid
58-97-9,27416-86-0

5'-Uridylic Acid

5'-adenosine monophosphate
61-19-8,24937-83-5,67583-85-1

5'-adenosine monophosphate

Guanosine 5'-monophosphate
85-32-5

Guanosine 5'-monophosphate

Conditions
Conditions Yield
With barley roots 5'-phosphodiesterase; at 70 ℃; for 0.5h; pH=5; aq. acetate buffer; Enzymatic reaction;
 
A(2'p5'A)3'p5'U

A(2'p5'A)3'p5'U

5'-Uridylic Acid
58-97-9,27416-86-0

5'-Uridylic Acid

5'-adenosine monophosphate
61-19-8,24937-83-5,67583-85-1

5'-adenosine monophosphate

Conditions
Conditions Yield
With SVP (1 unit); In water; at 37 ℃; for 12h; Product distribution; HPLC analysis; no reaction with RNaseT2 or spleen phosphodiesterase;
 

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