24292-60-2
- Product Name：Triphosphopyridine nucleotide disodium salt
- Molecular Formula：C21H28N7Na2O17P3
- Purity：99%
- Molecular Weight：787.37
Product Details
Chinese Factory Supply Triphosphopyridine nucleotide disodium salt 24292-60-2 Powder
- Molecular Formula:C21H28N7Na2O17P3
- Molecular Weight:787.37
- Appearance/Colour:Yellowish powder
- Vapor Pressure:0.002-0.004Pa at 20-25℃
- Melting Point:175-178 °C
- PSA：402.71000
- Density:1.66g/cm3 at 20℃
- LogP:-0.30280
Triphosphopyridine nucleotide disodium salt 24292-60-2 Powder Usage
Triphosphopyridine nucleotide disodium salt is a coenzyme that is widely distributed in living matter, Participates in oxidation-reduction reactions. NADP is a substance in which nicotinic acid amide adenine dinucleotide and a phosphate molecule are bound by ester bond. It is a hydrogen receptor and can be used for the development and development of a variety of in vitro diagnostic reagents.
InChI:InChI=1/C21H28N7O17P3.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;/q;2*+1/p-2/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1
Triphosphopyridine nucleotide disodium salt Relevant articles
Electron transfer by ferredoxin: NADP+ reductase. Rapid-reaction evidence for participation of a ternary complex.
C J Batie, H Kamin
Journal of Biological Chemistry, 1984
In the absence of NADP+, reduction of ferredoxin:NADP+ reductase by Fd was much slower than the catalytic rate: 37-80 s-1 versus at least 445 e-s-1; dissociation of oxidized spinach ferredoxin (Fdox) from one-electron reduced ferredoxin:NADP+ reductase (FNRsq) limited the reduction of FNR. The catalytic rate of Fd to NADP+ electron transfer, as well as the rates of electron transfer from Fd to FNR, and from FNR to NADP+ were decreased when the reactants were in D2O; diaphorase activity was unaffected by solvent. On the basis of the data presented, a scheme for the catalytic mechanism of catalysis by FNR is presented.
Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent
Tomonori Aoyama, Yong-Han Paik, Sumio Watanabe, Benoît Laleu, Francesca Gaggini, Laetitia Fioraso-Cartier, Sophie Molango, Freddy Heitz, Cédric Merlot, Cédric Szyndralewiez, Patrick Page, David A. Brenner
HEPATOLOGY, Volume56, Issue6 December 2012 Pages 2316-2327
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) generates reactive oxygen species (ROS) in hepatic stellate cells (HSCs) during liver fibrosis. Expression of NOX isoforms is increased in patients with pulmonary, renal, and liver fibrosis.
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